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MRI guided focal laser ablation map

This is an outpatient, minimally invasive treatment for prostate cancer that combines a cutting edge MRI and a state of the art, FDA cleared medical laser.

Advantages over surgery (radical prostatectomy):

  • Minimally invasive
  • Outpatient procedure
  • No general anesthesia
  • Rapid recovery
  • Low risk of erectile dysfunction
  • Low risk of urinary incontinence
  • Repeatable (if necessary)

3T multiparametric MRI offers unparalleled visualization of prostate cancer, allowing us to precisely target the cancer with a laser system measuring just 1.85 mm in diameter. We measure the temperature with MRI thermometry, giving real time heating information to allow Dr. Karamanian to protect vital structures. Studies have shown that our laser is extremely precise, down to 1 mm, which is very important when considering that the neurovascular bundle responsible for erections runs within a 2-4 millimeters of the edge of the prostate.

The cancer is ablated (destroyed with heat), without undergoing radical surgery and minimizing damage to the neurovascular bundle and urethra. The patient goes home a few hours after the procedure. Many of our patients have told us that just two days after the procedure, they were back to normal. We perform our ablations under conscious sedation (carefully monitored, powerful intravenous pain and anxiety medications) to minimize pain and anxiety.

Our Workup, Treatment, and Follow-up Protocol

  1. We look at your entire prostate health picture including your PSA, pathology results, MRI, and your personal treatment goals and desires.
  2. Based on the MRI, we create a prostate map, outline where the cancer is located, whether or not it appears confined to the prostate, and its proximity to vital structures. Putting all the pieces together, we give a recommendation regarding whether or not you are a good candidate for focal laser ablation (FLA). The good news is that about 4 out of 5 new diagnoses of prostate cancer are in the local stage, usually amenable to focal treatment.
  3. If you are a good candidate for FLA and choose to proceed, we perform the procedure in our 3T MRI location in Houston, Texas. Please download MRI Guided Focal Laser Ablation for Prostate Cancer: What to expect for more information about what to expect on the day of the procedure.
  4. We provide you with a detailed and personalized follow-up plan.

Suggested Questions

Before choosing a center for your focal prostate cancer treatment, consider asking the physician: 1) do you use a 3T MRI, an inferior 1.5T MRI, or no MRI during the procedure to guide the treatment and minimize collateral damage, 2) have you completed an ACGME certified interventional radiology fellowship or completed a non-ACGME certified fellowship, 3) do you use intravenous conscious sedation to minimize pain and anxiety during the procedure, and 4) do you use capnography as part of your patient monitoring to increase safety?



PLEASE NOTE: The information contained on this webpage is general educational information. It does not replace the need for personal evaluation, discussion of risks, benefits and alternatives of different treatment options, and professional medical care by Dr. Karamanian or another qualified, licensed physician.

Video: Prostate MRI & MRI guided Focal Laser Ablation for Prostate Cancer

Contact us today at (844) MENS-MRI or Request a Consultation